Making a Wiki for my lab group (in Off-topic)

My advisor wants our lab to have an internal wiki in order to make information we have available to all group members. I have been chosen to make this wiki, but am not sure what software to choose or where to start. An suggestions from the community are welcome, but I would prefer to hear from people who currently use an internal wiki.

Things my wiki must be able to do easily:

Primary

Store .pdf files and Endnote libraries for all our our literature (background stuff for various projects)

Secondary
Store slide presentations that will be used to educate future group members

That's not a wiki, that's a document management system...

He is obsessed with the 'buzz word' wiki. If a document management system is what we need can you refer me to one? I'll just name it 'wiki.'

We have several MS Sharepoint sites in our company. Pretty easy to setup and maintain.

Here is one using LAMP: http://en.wikipedia.org/wiki/KnowledgeTree I don't know if there are many others in this sphere, as it's a big "money maker" for lots of people.

I have a friend who just installed Plone for his department. The other big open-source ones are Drupal and Joomla.

All of them are a fair amount of work to customize. My friend went with Plone primarily because it has by far the best security record.

Plone is pretty sweet once you get up and running, but thats the tricky part.. At my last job, they had Plone setup to do some CMS stuff, but the client it was setup for didn't get how to use it (even though I found it surprisingly easy to use). And besides that it had stability issues with the plone deamon staying awake.. But it might have just been all the customizations we did to it.